Revue: | Anais da Academia Brasileira de Ciencias |
Base de datos: | PERIÓDICA |
Número de sistema: | 000418016 |
ISSN: | 0001-3765 |
Autores: | Dani, Caroline1 Andreazza, Ana Cristina2 Goncalves, Carlos Alberto3 Kapizinski, Flavio3 Henriques, Joao A.P1 Salvador, Mirian1 |
Instituciones: | 1Universidade de Caxias do Sul, Instituto de Biotecnologia, Caxias do Sul, Rio Grande do Sul. Brasil 2University of Toronto, Department of Psychiatry, Toronto, Ontario. Canadá 3Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul. Brasil |
Año: | 2017 |
Periodo: | Mar |
Volumen: | 89 |
Número: | 1 |
Paginación: | 155-162 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, aplicado |
Resumen en inglés | Several studies have shown that a high consumption of vegetables and fruits is consistently associated with a low risk of oxidative stress-induced diseases, which includes some degenerative diseases such as amyotrophic lateral sclerosis, Alzheimer and Parkinson. Therefore, the objective of this study is to verify the effects of conventional and organic grape juice in the modulation of the neurotrophic factor (BDNF) and astrocytic markers protein (S100B) in hippocampus and frontal cortex of Wistar rats. In this study, 24 male Wistar rats were divided into three groups. To the first one, it was given organic purple grape juice; to the second, conventional grape juice, while the last one received only saline. After 30 days, all rats were sacrificed and hippocampus and frontal cortex were dissected. The animals that received organic and conventional grape juice showed, in frontal cortex, an elevated BNDF levels in relation to saline group. However, S100B levels did not change. These results showed that grape juices are able to modulate important marker in brain tissue, and could be an important factor to prevent brain diseases |
Disciplinas: | Biología |
Palabras clave: | Fisiología animal, Jugo de uva, Polifenoles, Neuroprotección, Cerebro, Ratas |
Keyword: | Animal physiology, Grape juice, Polyphenols, Neuroprotection, Brain, Rats |
Texte intégral: | Texto completo (Ver HTML) |