Toxicological evaluation of the plant Xanthium strumarium in pigs in Zimbabwe



Document title: Toxicological evaluation of the plant Xanthium strumarium in pigs in Zimbabwe
Journal: The journal of venomous animals and toxins
Database: PERIÓDICA
System number: 000298617
ISSN: 0104-7930
Authors: 1
2
Institutions: 1University of Zimbabwe, Faculty of Veterinary Science, Mount Pleasant, Harare. Zimbabwe
2Central Veterinary Research & Diagnostic Laboratory, Causeway, Harare. Zimbabwe
Year:
Volumen: 4
Number: 2
Pages: 113-119
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract Major clinical signs were depression, vomiting, abdominal pain, weakness, recumbency, paddling convulsions terminating in death from 6 to 96 hours after ingestion. Gross pathological findings included ascites with fibrin strands, enlarged, congested and friable livers with accentuation of lobulation on the capsule. Microscopically, acute hepatic congestion and hemorrhage, centrilobular hepatocyte necrosis, with occasional binucleation together with discoid lysis of skeletal and cardiac muscle fibers were remarkable changes. Binucleation of hepatocytes and degenerative changes in active muscles have not been reported before in relation to cocklebur plant toxicosis. These findings suggest that X. strumarium is a potential cause of sudden death in pigs extensively reared in Zimbabwe
Disciplines: Biología
Keyword: Angiospermas,
Mamíferos,
Toxicología,
Toxicosis,
Cerdos,
Congestión hepática,
Xanthium strumarium
Keyword: Biology,
Angiosperms,
Mammals,
Toxicology,
Toxicosis,
Pigs,
Hepatic congestion,
Xanthium strumarium
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