| Journal: | The journal of venomous animals and toxins |
| Database: | PERIÓDICA |
| System number: | 000298585 |
| ISSN: | 0104-7930 |
| Authors: | Stanilova, S1 Zhelev, Z Matev, I2 |
| Institutions: | 1Thracian University of Stara Zagora, Medical Faculty, Stara Zagora. Bulgaria 2Thracian University of Stara Zagora, Zootechnic Faculty, Stara Zagora. Bulgaria |
| Year: | 1997 |
| Volumen: | 3 |
| Number: | 1 |
| Pages: | 37-42 |
| Country: | Brasil |
| Language: | Inglés |
| Document type: | Nota breve o noticia |
| Approach: | Experimental |
| English abstract | The present study demonstrates that Vipera ammodytes venom is a potent inhibitor of human complement activation. Crude venom was fractionated by ion-exchange chromatography and each fraction was then tested for proteolytic, hemolytic and anti-complement activities. Three peaks decreased the hemolytic activity of human serum when measured using assays for the classical and alternative pathways of activation. One of the anti-complement peaks contains a protease capable of cleaving the C3 component of complement |
| Disciplines: | Biología |
| Keyword: | Inmunología, Reptiles, Veneno de víbora, Complemento, Vipera ammodytes, Viperidae |
| Keyword: | Biology, Immunology, Reptiles, Snake venom, Complement, Vipera ammodytes, Viperidae |
| Full text: | Texto completo (Ver HTML) |
