Revue: | The journal of venomous animals and toxins |
Base de datos: | PERIÓDICA |
Número de sistema: | 000298585 |
ISSN: | 0104-7930 |
Autores: | Stanilova, S1 Zhelev, Z Matev, I2 |
Instituciones: | 1Thracian University of Stara Zagora, Medical Faculty, Stara Zagora. Bulgaria 2Thracian University of Stara Zagora, Zootechnic Faculty, Stara Zagora. Bulgaria |
Año: | 1997 |
Volumen: | 3 |
Número: | 1 |
Paginación: | 37-42 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Nota breve o noticia |
Enfoque: | Experimental |
Resumen en inglés | The present study demonstrates that Vipera ammodytes venom is a potent inhibitor of human complement activation. Crude venom was fractionated by ion-exchange chromatography and each fraction was then tested for proteolytic, hemolytic and anti-complement activities. Three peaks decreased the hemolytic activity of human serum when measured using assays for the classical and alternative pathways of activation. One of the anti-complement peaks contains a protease capable of cleaving the C3 component of complement |
Disciplinas: | Biología |
Palabras clave: | Inmunología, Reptiles, Veneno de víbora, Complemento, Vipera ammodytes, Viperidae |
Keyword: | Biology, Immunology, Reptiles, Snake venom, Complement, Vipera ammodytes, Viperidae |
Texte intégral: | Texto completo (Ver HTML) |