| Journal: | Revista de investigación clínica |
| Database: | PERIÓDICA |
| System number: | 000453036 |
| ISSN: | 0034-8376 |
| Authors: | Maggiani Aguilera, Pablo1 Hernández Estrada, Sergio1 Cano Cervantes, José H1 Chávez Iñiguez, Jonathan S3 Pérez Flores, Christian2 Díaz Avedaño, Odette del C1 Oseguera Vizcaíno, María C2 Matías Carmona, Mayra1 Ovando Morga, Daniel F1 Ramírez Ramírez, María G1 Navarro Blackaller, Guillermo3 Covarrubias Velasco, Marco A2 Torres Mayorga, José A2 Gómez Navarro, Benjamín2 García García, Guillermo2 |
| Institutions: | 1Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Ciudad de México. México 2Hospital Civil de Guadalajara Fray Antonio Alcalde, Unidad de Trasplante Renal, Guadalajara, Jalisco. México 3Universidad de Guadalajara, Centro de Ciencias de la Salud, Guadalajara, Jalisco. México |
| Year: | 2021 |
| Season: | Jul-Ago |
| Volumen: | 73 |
| Number: | 4 |
| Pages: | 216-221 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Background: The impact of donor quality on post-kidney transplant survival may vary by candidate condition. Objective: Analyzing the combined use of the Kidney Donor Profile Index (KDPI) and the estimated post-transplant survival (EPTS) scale and their correlation with the estimated glomerular filtration rate (eGFR) decline in deceased-donor kidney recipients (DDKR). Methods: This was a retrospective, observational cohort study. We included DDKRs between 2015 and 2017 at a national third-level hospital. Results: We analyzed 68 DDKR. The mean age at transplant was 41 ± 14 years, 47 (69%) had sensitization events, 18 (26%) had delayed graft function, and 16 (23%) acute rejection. The graft survival at 12 and 36 months was 98.1% (95% CI 94-100) and 83.7% (95% CI 65-100), respectively. The Pearson correlation coefficient between the percentage reduction in the annual eGFR and the sum of EPTS and KDPI scales was r = 0.61, p < 0.001. The correlation coefficient between the percentage reduction in the annual eGFR and the EPTS and KDPI scales separately was r = 0.55, p < 0.001, and r = 0.53, p < 0.001, respectively. Conclusions: The sum of EPTS and KDPI scales can provide a better donor-recipient relationship and has a moderately positive correlation with the decrease in eGFR in DDKR |
| Disciplines: | Medicina |
| Keyword: | Nefrología, Cirugía, Trasplante de riñón, Donadores vivos, Tasa de filtración glomerular, Rechazo de injerto, Sobrevivencia |
| Keyword: | Nephrology, Surgery, Kidney transplantation, Living donors, Glomerular filtration rate, Graft rejection, Survival |
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