The Sum of Kidney Donor Profile Index and Estimated Post-Transplant Survival Scale and Their Correlation with eGFR Decline in Deceased Donor Kidney Recipients
Título del documento: The Sum of Kidney Donor Profile Index and Estimated Post-Transplant Survival Scale and Their Correlation with eGFR Decline in Deceased Donor Kidney Recipients
Revista: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000453036
ISSN: 0034-8376
Autores: 1
1
1
3
2
1
2
1
1
1
3
2
2
2
2
Instituciones: 1Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Ciudad de México. México
2Hospital Civil de Guadalajara Fray Antonio Alcalde, Unidad de Trasplante Renal, Guadalajara, Jalisco. México
3Universidad de Guadalajara, Centro de Ciencias de la Salud, Guadalajara, Jalisco. México
Año:
Periodo: Jul-Ago
Volumen: 73
Número: 4
Paginación: 216-221
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Background: The impact of donor quality on post-kidney transplant survival may vary by candidate condition. Objective: Analyzing the combined use of the Kidney Donor Profile Index (KDPI) and the estimated post-transplant survival (EPTS) scale and their correlation with the estimated glomerular filtration rate (eGFR) decline in deceased-donor kidney recipients (DDKR). Methods: This was a retrospective, observational cohort study. We included DDKRs between 2015 and 2017 at a national third-level hospital. Results: We analyzed 68 DDKR. The mean age at transplant was 41 ± 14 years, 47 (69%) had sensitization events, 18 (26%) had delayed graft function, and 16 (23%) acute rejection. The graft survival at 12 and 36 months was 98.1% (95% CI 94-100) and 83.7% (95% CI 65-100), respectively. The Pearson correlation coefficient between the percentage reduction in the annual eGFR and the sum of EPTS and KDPI scales was r = 0.61, p < 0.001. The correlation coefficient between the percentage reduction in the annual eGFR and the EPTS and KDPI scales separately was r = 0.55, p < 0.001, and r = 0.53, p < 0.001, respectively. Conclusions: The sum of EPTS and KDPI scales can provide a better donor-recipient relationship and has a moderately positive correlation with the decrease in eGFR in DDKR
Disciplinas: Medicina
Palabras clave: Nefrología,
Cirugía,
Trasplante de riñón,
Donadores vivos,
Tasa de filtración glomerular,
Rechazo de injerto,
Sobrevivencia
Keyword: Nephrology,
Surgery,
Kidney transplantation,
Living donors,
Glomerular filtration rate,
Graft rejection,
Survival
Texto completo: Texto completo (Ver HTML) Texto completo (Ver PDF)