| Journal: | Revista de investigación clínica |
| Database: | PERIÓDICA |
| System number: | 000453174 |
| ISSN: | 0034-8376 |
| Authors: | Ochoa Hein, Eric1 Rajme López, Sandra2 Leal Morán, Patricia E1 Vargas Fernández, Abril T1 González Lara, María F2 Alberto Hernández, María F3 Bustos Román, Daniel E3 Valverde Ramos, Lirio N3 Ramos Cervantes, Pilar2 Cervantes Villar, Luz E2 Ibarra González, Violeta2 Ponce de León, Alfredo2 Galindo Fraga, Arturo1 Kershenobich Stalnikowitz, David4 Sifuentes Osornio, José5 |
| Institutions: | 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Epidemiología Hospitalaria, Ciudad de México. México 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Enfermedades Infecciosas,, Ciudad de México. México 3Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección General de Epidemiología, Ciudad de México. México 4Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección General, Ciudad de México. México 5Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección Médica, Ciudad de México. México |
| Year: | 2021 |
| Season: | Mar-Abr |
| Volumen: | 73 |
| Number: | 2 |
| Pages: | 65-71 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Background: Risk factors for coronavirus disease (COVID-19) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) asymptomatic carriage (AC) in healthcare workers (HCWs) have been scarcely characterized. Objective: The objective of the study was to study factors associated with COVID-19 and AC in HCWs of a COVID-19 academic medical center. Methods: This is a case-control study. Cases were either symptomatic or asymptomatic HCWs with a positive SARS-CoV-2 polymerase chain reaction (PCR) test result between March 16 and May 21 of 2020. Adjusted odds ratios (aOR) were calculated by means of multivariable logistic regression. In addition, each subject was followed for 14 days to inform outcomes. Results: One hundred thirty of 249 (52.2%) symptomatic HCWs had COVID-19; 10 were hospitalized but none died. Of 987 asymptomatic HCWs, 37 (3.7%) were AC; 6 of the remaining 950 asymptomatic HCWs with a negative PCR test result were found to be presymptomatic COVID-19 cases the following 14 days. Nurses were more frequently present in the COVID-19 group (51.5% vs. 37.0%), but multivariable analysis rendered non-significant results. After adjustment for age, comorbidities, and working place, factors found to be associated with AC were: working in wards as a nurse (aOR = 9.19, 95% confidence interval [CI] = 1.05-80.22, p = 0.045), kitchen personnel (aOR = 4.09, 95% CI = 1.55-10.83, p = 0.005), and being a physician (aOR = 0.12, 95% CI = 0.03-0.54, p = 0.006). Conclusions: HCW category was the predominant factor associated with AC of SARS-CoV-2 in this study |
| Disciplines: | Medicina |
| Keyword: | Neumología, Microbiología, Hospitales, COVID-19, SARS-CoV-2, Personal de salud, Portadores asintomáticos, Factores de riesgo |
| Keyword: | Pneumology, Microbiology, Hospitals, COVID-19, SARS-CoV-2, Health personnel, Asymptomatic carriers, Risk factors |
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