Factors Associated with COVID-19 and Asymptomatic Carriage in Healthcare Workers of a COVID-19 Hospital



Título del documento: Factors Associated with COVID-19 and Asymptomatic Carriage in Healthcare Workers of a COVID-19 Hospital
Revista: Revista de investigación clínica
Base de datos: PERIÓDICA
Número de sistema: 000453174
ISSN: 0034-8376
Autores: 1
2
1
1
2
3
3
3
2
2
2
2
1
4
5
Instituciones: 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Epidemiología Hospitalaria, Ciudad de México. México
2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Enfermedades Infecciosas,, Ciudad de México. México
3Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección General de Epidemiología, Ciudad de México. México
4Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección General, Ciudad de México. México
5Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dirección Médica, Ciudad de México. México
Año:
Periodo: Mar-Abr
Volumen: 73
Número: 2
Paginación: 65-71
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Background: Risk factors for coronavirus disease (COVID-19) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) asymptomatic carriage (AC) in healthcare workers (HCWs) have been scarcely characterized. Objective: The objective of the study was to study factors associated with COVID-19 and AC in HCWs of a COVID-19 academic medical center. Methods: This is a case-control study. Cases were either symptomatic or asymptomatic HCWs with a positive SARS-CoV-2 polymerase chain reaction (PCR) test result between March 16 and May 21 of 2020. Adjusted odds ratios (aOR) were calculated by means of multivariable logistic regression. In addition, each subject was followed for 14 days to inform outcomes. Results: One hundred thirty of 249 (52.2%) symptomatic HCWs had COVID-19; 10 were hospitalized but none died. Of 987 asymptomatic HCWs, 37 (3.7%) were AC; 6 of the remaining 950 asymptomatic HCWs with a negative PCR test result were found to be presymptomatic COVID-19 cases the following 14 days. Nurses were more frequently present in the COVID-19 group (51.5% vs. 37.0%), but multivariable analysis rendered non-significant results. After adjustment for age, comorbidities, and working place, factors found to be associated with AC were: working in wards as a nurse (aOR = 9.19, 95% confidence interval [CI] = 1.05-80.22, p = 0.045), kitchen personnel (aOR = 4.09, 95% CI = 1.55-10.83, p = 0.005), and being a physician (aOR = 0.12, 95% CI = 0.03-0.54, p = 0.006). Conclusions: HCW category was the predominant factor associated with AC of SARS-CoV-2 in this study
Disciplinas: Medicina
Palabras clave: Neumología,
Microbiología,
Hospitales,
COVID-19,
SARS-CoV-2,
Personal de salud,
Portadores asintomáticos,
Factores de riesgo
Keyword: Pneumology,
Microbiology,
Hospitals,
COVID-19,
SARS-CoV-2,
Health personnel,
Asymptomatic carriers,
Risk factors
Texto completo: Texto completo (Ver HTML) Texto completo (Ver PDF)