Synthesis and characterization of novel α-monomers of peptide nucleic acid
Document title: Synthesis and characterization of novel α-monomers of peptide nucleic acid
Journal: Journal of applied research and technology
Database: PERIÓDICA
System number: 000424094
ISSN: 1665-6423
Authors: 1
Institutions: 1Galgotias University, School of Basic and Applied Sciences, Greater Noida, Uttar Pradesh. India
Year:
Season: Abr
Volumen: 15
Number: 2
Country: México
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract This paper reports the synthesis and characterization of two novel modified α-monomers of peptide nucleic acid containing thymine and cytosine nucleobases. These novel monomers have been synthesized by the incorporation of thiol moiety in the side chain of peptide nucleic acid backbone. These novel α-monomers have been identified with different spectroscopic techniques, notably infra-red spectroscopy, 1H and 13C nuclear magnetic resonance spectroscopy, supported by mass spectrometry
Disciplines: Química
Keyword: Bioquímica,
Química analítica,
Péptidos,
Acidos nucléicos,
Alfa-monómeros,
Tioles,
Citocinas,
Timina
Keyword: Biochemistry,
Analytical chemistry,
Peptides,
Nucleic acids,
Thiols,
Cytosines,
Thymine,
Αlpha-monomers
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