Synthesis and characterization of novel α-monomers of peptide nucleic acid
Título del documento: Synthesis and characterization of novel α-monomers of peptide nucleic acid
Revue: Journal of applied research and technology
Base de datos: PERIÓDICA
Número de sistema: 000424094
ISSN: 1665-6423
Autores: 1
Instituciones: 1Galgotias University, School of Basic and Applied Sciences, Greater Noida, Uttar Pradesh. India
Año:
Periodo: Abr
Volumen: 15
Número: 2
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés This paper reports the synthesis and characterization of two novel modified α-monomers of peptide nucleic acid containing thymine and cytosine nucleobases. These novel monomers have been synthesized by the incorporation of thiol moiety in the side chain of peptide nucleic acid backbone. These novel α-monomers have been identified with different spectroscopic techniques, notably infra-red spectroscopy, 1H and 13C nuclear magnetic resonance spectroscopy, supported by mass spectrometry
Disciplinas: Química
Palabras clave: Bioquímica,
Química analítica,
Péptidos,
Acidos nucléicos,
Alfa-monómeros,
Tioles,
Citocinas,
Timina
Keyword: Biochemistry,
Analytical chemistry,
Peptides,
Nucleic acids,
Thiols,
Cytosines,
Thymine,
Αlpha-monomers
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