Effect of ACTH4-10pro8-gly9-pro10 on malondialdehyde and F2-isoprostane 15(S)-8-iso-PGF2a expression in rat spinal cord injury



Título del documento: Effect of ACTH4-10pro8-gly9-pro10 on malondialdehyde and F2-isoprostane 15(S)-8-iso-PGF2a expression in rat spinal cord injury
Revista: Gaceta médica de Caracas
Base de datos:
Número de sistema: 000595987
ISSN: 2739-0012
Autores: 1
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1
2
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3
Instituciones: 1Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, East Java. Indonesia
2Universitas Airlangga, Faculty of Medicine, Surabaya, East Java. Indonesia
3Universitas Nahdlatul Ulama Surabaya, Faculty of Medicine, Surabaya, East Java. Indonesia
Año:
Volumen: 131
Número: 4
País: Venezuela
Idioma: Inglés
Tipo de documento: Artículo
Resumen en español Background: Spinal cord injury (SCI) is damage to the spinal cord caused mainly by trauma resulting in major motor, sensory, and autonomic dysfunctions. This experimental study aims to assess the effect of ACTH4-10Pro8-Gly9-Pro10 administration in rats with mild and severe compression injuries on the levels of malondialdehyde and F2-isoprostane 15(S)-8-iso-PGF2α levels. Methods: Mild and severe spinal cord compression was performed on 27 subjects. They were divided into three groups of samples with control included, 3 and 6 h after the injury.
Disciplinas: Medicina,
Medicina
Palabras clave: Medicina experimental,
Neurología
Keyword: Experimental medicine,
Neurology
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