SVM-RFE-ED: A Novel SVM-RFE based on Energy Distance for Gene Selection and Cancer Diagnosis



Document title: SVM-RFE-ED: A Novel SVM-RFE based on Energy Distance for Gene Selection and Cancer Diagnosis
Journal: Computación y sistemas
Database:
System number: 000560152
ISSN: 1405-5546
Authors: 1
2
Institutions: 1Université des Sciences et de la Technologie d'Oran Mohamed Boudiaf, Oran. Argelia
2Taif University, College of Computers and Information Technology, Taif. Arabia Saudita
Year:
Season: Abr-Jun
Volumen: 22
Number: 2
Pages: 675-683
Country: México
Language: Inglés
Document type: Artículo
English abstract Microarray expression data has been a very active research field and an indispensable tool for cancer diagnosis. The microarray expression dataset contains thousands of genes and selecting a subset of informative genes is a primordial preprocessing step for improving the cancer classification. Support Vector Machine Recursive Feature Elimination (SVM-RFE) is one of the popular and effective gene selection approaches. However, SVM-RFE attempts to find the best possible combination for classification and does not take into account the ability of class separability for each gene. In this paper, a novel SVM-RFE based on energy distance (ED) and called SVM-RFE-ED is proposed to overcome the limitation of standard SVM-RFE. The aims of our study are to achieve a high classification accuracy rate and improve the classification model. The experimentation is conducted on five widely used datasets. Experimental results indicate that the proposed approach SVM-RFE-ED provides good results and achieve a high classification accuracy rate using a small number of genes.
Disciplines: Ciencias de la computación
Keyword: Inteligencia artificial
Keyword: Cancer diagnosis,
Support vector machine,
Recursive feature elimination,
Gene selection,
Energy distance,
Classification,
Artificial intelligence
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