SVM-RFE-ED: A Novel SVM-RFE based on Energy Distance for Gene Selection and Cancer Diagnosis



Título del documento: SVM-RFE-ED: A Novel SVM-RFE based on Energy Distance for Gene Selection and Cancer Diagnosis
Revista: Computación y sistemas
Base de datos:
Número de sistema: 000560152
ISSN: 1405-5546
Autors: 1
2
Institucions: 1Université des Sciences et de la Technologie d'Oran Mohamed Boudiaf, Oran. Argelia
2Taif University, College of Computers and Information Technology, Taif. Arabia Saudita
Any:
Període: Abr-Jun
Volum: 22
Número: 2
Paginació: 675-683
País: México
Idioma: Inglés
Tipo de documento: Artículo
Resumen en inglés Microarray expression data has been a very active research field and an indispensable tool for cancer diagnosis. The microarray expression dataset contains thousands of genes and selecting a subset of informative genes is a primordial preprocessing step for improving the cancer classification. Support Vector Machine Recursive Feature Elimination (SVM-RFE) is one of the popular and effective gene selection approaches. However, SVM-RFE attempts to find the best possible combination for classification and does not take into account the ability of class separability for each gene. In this paper, a novel SVM-RFE based on energy distance (ED) and called SVM-RFE-ED is proposed to overcome the limitation of standard SVM-RFE. The aims of our study are to achieve a high classification accuracy rate and improve the classification model. The experimentation is conducted on five widely used datasets. Experimental results indicate that the proposed approach SVM-RFE-ED provides good results and achieve a high classification accuracy rate using a small number of genes.
Disciplines Ciencias de la computación
Paraules clau: Inteligencia artificial
Keyword: Cancer diagnosis,
Support vector machine,
Recursive feature elimination,
Gene selection,
Energy distance,
Classification,
Artificial intelligence
Text complet: Texto completo (Ver HTML) Texto completo (Ver PDF)