Antibiotic susceptibility patterns of bacterial isolates of patients with upper respiratory tract infections
Document title: Antibiotic susceptibility patterns of bacterial isolates of patients with upper respiratory tract infections
Journal: Brazilian Journal of Pharmaceutical Sciences
Database: PERIÓDICA
System number: 000451734
ISSN: 1984-8250
Authors: 1
1
1
1
2
2
Institutions: 1University of Balochistan, Faculty of Pharmacy & Health Sciences, Quetta, Baluchistán. Pakistán
2University of the Punjab, University College of Pharmacy, Lahore, Punjab. Pakistán
Year:
Volumen: 58
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Aplicado, descriptivo
English abstract To evaluate the antibiotic susceptibility patterns in URTIs reporting to tertiary hospitals of Lahore. A cross-sectional study employing 259 culture sensitivity reports obtained from tertiary care hospitals of Lahore. Using SPSS, descriptive statistics were used to estimate frequencies and percentages. In URTIs, S. aureus (5%) was the frequent gram-positive isolate followed by MRSA (1.5%) and MSSA (1.5%), while P. aeruginosa (15.8%) was the prevalent gram-negative isolate followed by Klebsiella (13.1%) and E. coli (6.9%). Against P. aeruginosa, ceftazidime (7.7%), cefuroxime/ceftriaxone (4.6%), amoxicillin (4.3%) and ciprofloxacin (4.2%), were tested resistant, while imipenem (11.2%), ciprofloxacin (9.2%), amikacin (9.2%), meropenem/ levofloxacin/gentamicin (8.1%) and piptaz (6.9%) were found sensitive. Against Klebsiella, carbepenems (7.3%), amikacin (6.5%), ciprofloxacin (5.4%) and gentamicin (5%) were tested sensitive, whereas, ceftazidime (8.5%), ceftriaxone (5.8%), cefaclor (5.5%), ampicillin (4.6%), co-amoxiclave (4.2%) and ciftazidime/ciprofloxacin (3.8%) were found resistant. Overall, imipenem (35%), meropenem (30.8%) and amikacin (31.9%) were the three most sensitive antibiotics, while ceftazidime (25.4%), ceftriaxone (19.2%) and ampicillin (18.5%) were the three most resistant antibiotics. Data suggested that P.aeruginosa and Klebsiella, were the most frequent bacterial isolates in URTIs of Lahore. These isolates were resistant to ampicillin, cefuroxime and ceftazidime, but were sensitive to carbapenem and aminoglycosides
Disciplines: Medicina
Keyword: Neumología,
Microbiología,
Farmacología,
Infecciones respiratorias,
Pseudomonas aeruginosa,
Resistencia a fármacos,
Ceftazidima,
Amikacina
Keyword: Pneumology,
Microbiology,
Pharmacology,
Respiratory infections,
Pseudomonas aeruginosa,
Drug resistance,
Amikacin,
Ceftazidime
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