| Revista: | Brazilian Journal of Pharmaceutical Sciences |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000451734 |
| ISSN: | 1984-8250 |
| Autores: | Ullah, Kalim1 Baloch, Marvi1 Saleem, Fahad1 Khan, Ayaz Ali1 Saeed, Hamid2 Islam, Muhammad2 |
| Instituciones: | 1University of Balochistan, Faculty of Pharmacy & Health Sciences, Quetta, Baluchistán. Pakistán 2University of the Punjab, University College of Pharmacy, Lahore, Punjab. Pakistán |
| Año: | 2022 |
| Volumen: | 58 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Aplicado, descriptivo |
| Resumen en inglés | To evaluate the antibiotic susceptibility patterns in URTIs reporting to tertiary hospitals of Lahore. A cross-sectional study employing 259 culture sensitivity reports obtained from tertiary care hospitals of Lahore. Using SPSS, descriptive statistics were used to estimate frequencies and percentages. In URTIs, S. aureus (5%) was the frequent gram-positive isolate followed by MRSA (1.5%) and MSSA (1.5%), while P. aeruginosa (15.8%) was the prevalent gram-negative isolate followed by Klebsiella (13.1%) and E. coli (6.9%). Against P. aeruginosa, ceftazidime (7.7%), cefuroxime/ceftriaxone (4.6%), amoxicillin (4.3%) and ciprofloxacin (4.2%), were tested resistant, while imipenem (11.2%), ciprofloxacin (9.2%), amikacin (9.2%), meropenem/ levofloxacin/gentamicin (8.1%) and piptaz (6.9%) were found sensitive. Against Klebsiella, carbepenems (7.3%), amikacin (6.5%), ciprofloxacin (5.4%) and gentamicin (5%) were tested sensitive, whereas, ceftazidime (8.5%), ceftriaxone (5.8%), cefaclor (5.5%), ampicillin (4.6%), co-amoxiclave (4.2%) and ciftazidime/ciprofloxacin (3.8%) were found resistant. Overall, imipenem (35%), meropenem (30.8%) and amikacin (31.9%) were the three most sensitive antibiotics, while ceftazidime (25.4%), ceftriaxone (19.2%) and ampicillin (18.5%) were the three most resistant antibiotics. Data suggested that P.aeruginosa and Klebsiella, were the most frequent bacterial isolates in URTIs of Lahore. These isolates were resistant to ampicillin, cefuroxime and ceftazidime, but were sensitive to carbapenem and aminoglycosides |
| Disciplinas: | Medicina |
| Palabras clave: | Neumología, Microbiología, Farmacología, Infecciones respiratorias, Pseudomonas aeruginosa, Resistencia a fármacos, Ceftazidima, Amikacina |
| Keyword: | Pneumology, Microbiology, Pharmacology, Respiratory infections, Pseudomonas aeruginosa, Drug resistance, Amikacin, Ceftazidime |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
