| Journal: | Biotecnología aplicada |
| Database: | PERIÓDICA |
| System number: | 000353536 |
| ISSN: | 0864-4551 |
| Authors: | Nogueiras, Clara1 Spengler, Iraida1 Guerra, José O3 Ortiz, Yarelys2 Torres, Susana1 García, Trina H1 Romeu, Carlos R4 Regalado, Erik L5 González, Telce A6 Perera, Wilmer H7 Lacret, Radney1 |
| Institutions: | 1Universidad de La Habana, Facultad de Química, La Habana. Cuba 2Instituto de Investigaciones Fundamentales en Agricultura Tropical "Alejandro de Humboldt", Santiago de las Vegas, La Habana. Cuba 3Universidad Central "Marta Abreu" de Las Villas, Villa Clara. Cuba 4Instituto de Sanidad Vegetal, La Habana. Cuba 5Centro de Bioproductos Marinos, La Habana. Cuba 6Instituto de Investigaciones del Arroz, Bauta, La Habana. Cuba 7Instituto de Ecología y Sistemática, La Habana. Cuba |
| Year: | 2010 |
| Volumen: | 27 |
| Number: | 4 |
| Pages: | 314-318 |
| Country: | Cuba |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the “Centro de Estudios de Productos Naturales, CEPN” during the past ten years, highlighting on those with potential use as biomedical and agrochemicals. 15 plant species were studied; Agave brittoniana Trel. Subsp. brachypus A Álvarez de Zayas (Agavaceae); Juniperus barbadensis L. var. Lucayana (Britt.) RP Adams (Cupressaceae); Melia azedarach Linn. (Meliaceae); Tectona grandis Linn. f. (Lamiaceae); Lantana camara Linn. (Verbenaceae); Lantana trifolia Cham. (Verbenaceae); Citrus sinensis (Linn.) Osbeck cv Valencia (Rutaceae); Maytenus buxifolia (A Rich) Griseb (Celastraceae); Maytenus elaeodendroides Griseb (Celastraceae); Maytenus urquiolae B Mory (Celastraceae); Solanum americanum W. Mill (Solanaceae); Thalassia testudinum Kon. (Hydrocharitaceae); Sesbania rostrata Bremek & Oberm (Fabaceae); Pluchea carolinensis G Don (Asteraceae) and Ageratina havanensis (HB & K) RM King & Robinson (Asteraceae). By means of a bio-guided fractionation, isolated structures as well as semi-purified fractions were assayed as antioxidant, antiparasitic, antibiotic, insecticides, antifungal, and skin regenerating and healing effects. The strateg y employed allows us to discover novel secondary metabolites with potential for industrial development as pharmaceuticals and/or agrochemicals. Besides, in addition to the goal of discovering new bioactive agents |
| Disciplines: | Química, Biología |
| Keyword: | Fitoquímica, Metabolitos secundarios, Actividad biológica, Flavonoides, Compuestos fenólicos, Saponinas, Terpenoides, Quinonas |
| Keyword: | Chemistry, Biology, Phytochemistry, Secondary metabolites, Biological activity, Flavonoids, Phenolic compounds, Saponins, Terpenoids, Quinones |
| Full text: | Texto completo (Ver PDF) |
