Contribution to the phytochemical study and biological activity of plants of Cuban flora



Título del documento: Contribution to the phytochemical study and biological activity of plants of Cuban flora
Revista: Biotecnología aplicada
Base de datos: PERIÓDICA
Número de sistema: 000353536
ISSN: 0864-4551
Autores: 1
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Instituciones: 1Universidad de La Habana, Facultad de Química, La Habana. Cuba
2Instituto de Investigaciones Fundamentales en Agricultura Tropical "Alejandro de Humboldt", Santiago de las Vegas, La Habana. Cuba
3Universidad Central "Marta Abreu" de Las Villas, Villa Clara. Cuba
4Instituto de Sanidad Vegetal, La Habana. Cuba
5Centro de Bioproductos Marinos, La Habana. Cuba
6Instituto de Investigaciones del Arroz, Bauta, La Habana. Cuba
7Instituto de Ecología y Sistemática, La Habana. Cuba
Año:
Volumen: 27
Número: 4
Paginación: 314-318
País: Cuba
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the “Centro de Estudios de Productos Naturales, CEPN” during the past ten years, highlighting on those with potential use as biomedical and agrochemicals. 15 plant species were studied; Agave brittoniana Trel. Subsp. brachypus A Álvarez de Zayas (Agavaceae); Juniperus barbadensis L. var. Lucayana (Britt.) RP Adams (Cupressaceae); Melia azedarach Linn. (Meliaceae); Tectona grandis Linn. f. (Lamiaceae); Lantana camara Linn. (Verbenaceae); Lantana trifolia Cham. (Verbenaceae); Citrus sinensis (Linn.) Osbeck cv Valencia (Rutaceae); Maytenus buxifolia (A Rich) Griseb (Celastraceae); Maytenus elaeodendroides Griseb (Celastraceae); Maytenus urquiolae B Mory (Celastraceae); Solanum americanum W. Mill (Solanaceae); Thalassia testudinum Kon. (Hydrocharitaceae); Sesbania rostrata Bremek & Oberm (Fabaceae); Pluchea carolinensis G Don (Asteraceae) and Ageratina havanensis (HB & K) RM King & Robinson (Asteraceae). By means of a bio-guided fractionation, isolated structures as well as semi-purified fractions were assayed as antioxidant, antiparasitic, antibiotic, insecticides, antifungal, and skin regenerating and healing effects. The strateg y employed allows us to discover novel secondary metabolites with potential for industrial development as pharmaceuticals and/or agrochemicals. Besides, in addition to the goal of discovering new bioactive agents
Disciplinas: Química,
Biología
Palabras clave: Fitoquímica,
Metabolitos secundarios,
Actividad biológica,
Flavonoides,
Compuestos fenólicos,
Saponinas,
Terpenoides,
Quinonas
Keyword: Chemistry,
Biology,
Phytochemistry,
Secondary metabolites,
Biological activity,
Flavonoids,
Phenolic compounds,
Saponins,
Terpenoids,
Quinones
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