| Journal: | Biotecnología aplicada |
| Database: | PERIÓDICA |
| System number: | 000349779 |
| ISSN: | 0864-4551 |
| Authors: | Sarmiento, Luis1 Cabrera, Eduardo2 Díaz, Oscar2 Fonseca, Magile1 Molina, Gisela2 Cuba, Ileana2 Más, Pedro1 Heng, Lai1 Resik, Sonia1 |
| Institutions: | 1Instituto de Medicina Tropical "Pedro Kouri", Departamento de Virología, La Habana. Cuba 2Instituto Nacional de Endocrinología, Departamento de Inmunología de la Diabetes, La Habana. Cuba |
| Year: | 2009 |
| Volumen: | 26 |
| Number: | 4 |
| Pages: | 349-351 |
| Country: | Cuba |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Experimental, aplicado |
| English abstract | Enteroviruses have been examined for their possible role in the etiology of type 1 diabetes mellitus (T1DM) for nearly 40 years; however, the evidence remains inconclusive so far. This article provides new findings from Cuban studies suggesting the involvement of enteroviruses, either with the clinical T1DM onset or the pre-clinical stages of the β- cell autoimmunity in populations with low incidence of diabetes and high enteroviral circulation. Potential mechanisms of pathogenesis such as direct β- cell lysis and molecular mimicry are also discussed |
| Disciplines: | Medicina |
| Keyword: | Metabolismo, Inmunología, Diabetes, Autoinmunidad, Autoanticuerpos, Enterovirus |
| Keyword: | Medicine, Metabolism, Immunology, Diabetes, Autoimmunity, Autoantibodies, Enterovirus |
| Full text: | Texto completo (Ver PDF) |
