Association between enterovirus infection and type 1 diabetes: new findings from Cuban studies
Título del documento: Association between enterovirus infection and type 1 diabetes: new findings from Cuban studies
Revista: Biotecnología aplicada
Base de datos: PERIÓDICA
Número de sistema: 000349779
ISSN: 0864-4551
Autores: 1
2
2
1
2
2
1
1
1
Instituciones: 1Instituto de Medicina Tropical "Pedro Kouri", Departamento de Virología, La Habana. Cuba
2Instituto Nacional de Endocrinología, Departamento de Inmunología de la Diabetes, La Habana. Cuba
Año:
Volumen: 26
Número: 4
Paginación: 349-351
País: Cuba
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, aplicado
Resumen en inglés Enteroviruses have been examined for their possible role in the etiology of type 1 diabetes mellitus (T1DM) for nearly 40 years; however, the evidence remains inconclusive so far. This article provides new findings from Cuban studies suggesting the involvement of enteroviruses, either with the clinical T1DM onset or the pre-clinical stages of the β- cell autoimmunity in populations with low incidence of diabetes and high enteroviral circulation. Potential mechanisms of pathogenesis such as direct β- cell lysis and molecular mimicry are also discussed
Disciplinas: Medicina
Palabras clave: Metabolismo,
Inmunología,
Diabetes,
Autoinmunidad,
Autoanticuerpos,
Enterovirus
Keyword: Medicine,
Metabolism,
Immunology,
Diabetes,
Autoimmunity,
Autoantibodies,
Enterovirus
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