| Journal: | Annals of hepatology |
| Database: | PERIÓDICA |
| System number: | 000407468 |
| ISSN: | 1665-2681 |
| Authors: | Mattos, Angelo Zambam de1 Mattos, Angelo Alves de1 Méndez Sánchez, Nahum2 |
| Institutions: | 1Irmandade Santa Casa de Misericordia de Porto Alegre, Hospital Santa Rita, Porto Alegre, Rio Grande do Sul. Brasil 2Fundación Clínica Médica Sur, Unidad de Investigación Hepática, Ciudad de México. México |
| Year: | 2016 |
| Season: | Jul-Ago |
| Volumen: | 15 |
| Number: | 4 |
| Pages: | 474-481 |
| Country: | México |
| Language: | Inglés |
| Document type: | Artículo |
| Approach: | Analítico, descriptivo |
| English abstract | Renal failure in cirrhotic patients is a very severe condition. Hepatorenal syndrome has the worst prognosis among all causes of kidney failure in such patients. Hepatorenal syndrome is diagnosed especially in cirrhotic patients with ascites who develop loss renal function, despite diuretic suspension and volume expansion with albumin and for whom other causes of kidney injury have been excluded. Patients with hepatorenal syndrome should be treated with a vasoconstrictor in combination with albumin as a bridge to receiving a liver transplant. The vasoconstrictor of choice is terlipressin or noradrenaline. In spite of higher drug-related costs associated to terlipressin, initial evidence demonstrates that, considering all direct medical costs involved, the treatment strategy using terlipressin is probably more economical than that using noradrenaline |
| Disciplines: | Medicina |
| Keyword: | Gastroenterología, Nefrología, Terapéutica y rehabilitación, Síndrome hepatorrenal, Cirrosis hepática, Lesión renal aguda, Terlipresina, Noradrenalina, Albúmina |
| Keyword: | Medicine, Gastroenterology, Nephrology, Therapeutics and rehabilitation, Hepatorenal syndrome, Liver cirrhosis, Acute kidney injury, Terlipressin, Noradrenaline, Albumin |
| Full text: | Texto completo (Ver PDF) |
