Hepatorenal syndrome: Current concepts related to diagnosis and management



Título del documento: Hepatorenal syndrome: Current concepts related to diagnosis and management
Revista: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000407468
ISSN: 1665-2681
Autores: 1
1
2
Instituciones: 1Irmandade Santa Casa de Misericordia de Porto Alegre, Hospital Santa Rita, Porto Alegre, Rio Grande do Sul. Brasil
2Fundación Clínica Médica Sur, Unidad de Investigación Hepática, Ciudad de México. México
Año:
Periodo: Jul-Ago
Volumen: 15
Número: 4
Paginación: 474-481
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Renal failure in cirrhotic patients is a very severe condition. Hepatorenal syndrome has the worst prognosis among all causes of kidney failure in such patients. Hepatorenal syndrome is diagnosed especially in cirrhotic patients with ascites who develop loss renal function, despite diuretic suspension and volume expansion with albumin and for whom other causes of kidney injury have been excluded. Patients with hepatorenal syndrome should be treated with a vasoconstrictor in combination with albumin as a bridge to receiving a liver transplant. The vasoconstrictor of choice is terlipressin or noradrenaline. In spite of higher drug-related costs associated to terlipressin, initial evidence demonstrates that, considering all direct medical costs involved, the treatment strategy using terlipressin is probably more economical than that using noradrenaline
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Nefrología,
Terapéutica y rehabilitación,
Síndrome hepatorrenal,
Cirrosis hepática,
Lesión renal aguda,
Terlipresina,
Noradrenalina,
Albúmina
Keyword: Medicine,
Gastroenterology,
Nephrology,
Therapeutics and rehabilitation,
Hepatorenal syndrome,
Liver cirrhosis,
Acute kidney injury,
Terlipressin,
Noradrenaline,
Albumin
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