Tissue reaction and anti-biofilm action of new biomaterial composed of latex from Hancornia speciosa Gomes and silver nanoparticles
Document title: Tissue reaction and anti-biofilm action of new biomaterial composed of latex from Hancornia speciosa Gomes and silver nanoparticles
Journal: Anais da Academia Brasileira de Ciencias
Database: PERIÓDICA
System number: 000435804
ISSN: 0001-3765
Authors: 1
1
2
3
4
2
5
Institutions: 1Universidade do Sagrado Coracao, Bauru, Sao Paulo. Brasil
2Universidade de Sao Paulo, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Ribeirao Preto, Sao Paulo. Brasil
3Universidade Federal de Goias, Instituto Fisica, Goiania, Goias. Brasil
4Universidade Estadual de Goias, Anapolis, Goias. Brasil
5Universidade do Oeste Paulista, Presidente Prudente, Sao Paulo. Brasil
6Faculdade do Centro Oeste Paulista, Curso de Odontologia, Piratininga, Sao Paulo. Brasil
Year:
Volumen: 92
Number: 4
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract In this work, the natural latex extracted from Harconia speciosa was incorporated with silver nanoparticles (AgNP) to compose a functional biomaterial associating the intrinsic angiogenic activity of the latex and the antimicrobial activity of AgNP. Tissue reaction after subcutaneous implantation in dorsum of rats of membranes without AgNP and with 0.05%, 0.4% AgNP was compared at 3, 7 and 25 days. No statistically significant difference in the tissue response of the different biomaterials was observed, indicating that AgNP did not interfere with the inflammatory reaction (p > 0.05) or with the angiogenic activity of latex. Biomembranes were also tested against bacterial biofilm formation by Staphylococcus aureus and the antimicrobial activity of the new biomaterial can be found with bacteria crenation (0.05% AgNP) and no biofilm deposition (0.4% AgNP). Therefore, this biomaterial has interesting properties for the tissue repair process and may be feasible for future applications as dressing
Disciplines: Medicina
Keyword: Medicina experimental,
Látex,
Hancornia speciosa,
Angiogénesis,
Actividad antimicrobiana,
Biomembranas,
Biocompatibilidad,
Inflamación,
Nanopartículas de plata,
Apósitos
Keyword: Experimental medicine,
Latex,
Hancornia speciosa,
Angiogenesis,
Antimicrobial activity,
Biomembranes,
Biocompatibility,
Inflammation,
Silver nanoparticles,
Wound dressings
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