| Revista: | Anais da Academia Brasileira de Ciencias |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000435804 |
| ISSN: | 0001-3765 |
| Autors: | Bonete, Jéssica M1 Silva, Guilherme D1 Guidelli, Eder J2 Goncalves, Pablo J3 Almeida, Luciane M4 Baffa, Oswaldo2 Kinoshita, Angela5 |
| Institucions: | 1Universidade do Sagrado Coracao, Bauru, Sao Paulo. Brasil 2Universidade de Sao Paulo, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Ribeirao Preto, Sao Paulo. Brasil 3Universidade Federal de Goias, Instituto Fisica, Goiania, Goias. Brasil 4Universidade Estadual de Goias, Anapolis, Goias. Brasil 5Universidade do Oeste Paulista, Presidente Prudente, Sao Paulo. Brasil 6Faculdade do Centro Oeste Paulista, Curso de Odontologia, Piratininga, Sao Paulo. Brasil |
| Any: | 2020 |
| Volum: | 92 |
| Número: | 4 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | In this work, the natural latex extracted from Harconia speciosa was incorporated with silver nanoparticles (AgNP) to compose a functional biomaterial associating the intrinsic angiogenic activity of the latex and the antimicrobial activity of AgNP. Tissue reaction after subcutaneous implantation in dorsum of rats of membranes without AgNP and with 0.05%, 0.4% AgNP was compared at 3, 7 and 25 days. No statistically significant difference in the tissue response of the different biomaterials was observed, indicating that AgNP did not interfere with the inflammatory reaction (p > 0.05) or with the angiogenic activity of latex. Biomembranes were also tested against bacterial biofilm formation by Staphylococcus aureus and the antimicrobial activity of the new biomaterial can be found with bacteria crenation (0.05% AgNP) and no biofilm deposition (0.4% AgNP). Therefore, this biomaterial has interesting properties for the tissue repair process and may be feasible for future applications as dressing |
| Disciplines | Medicina |
| Paraules clau: | Medicina experimental, Látex, Hancornia speciosa, Angiogénesis, Actividad antimicrobiana, Biomembranas, Biocompatibilidad, Inflamación, Nanopartículas de plata, Apósitos |
| Keyword: | Experimental medicine, Latex, Hancornia speciosa, Angiogenesis, Antimicrobial activity, Biomembranes, Biocompatibility, Inflammation, Silver nanoparticles, Wound dressings |
| Text complet: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
