| Revue: | The journal of venomous animals and toxins |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000298768 |
| ISSN: | 0104-7930 |
| Autores: | Remuzgo, C1 Alvarez, M.P Rodríguez, E Lazo, F Yarlequé, A |
| Instituciones: | 1Universidad Nacional Mayor de San Marcos, Facultad de Ciencias Biológicas, Lima. Perú |
| Año: | 2002 |
| Volumen: | 8 |
| Número: | 1 |
| Paginación: | 161-167 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental |
| Resumen en inglés | Micrurus spixii venom was studied after fractionation by Sephadex G-100 SF gel filtration chromatography. Several enzymatic activities and biological effects were investigated in whole venom and fractions. The venom was resolved in four peaks in a range of about 73.2-10.7 kDa molecular weight. Alkaline phosphatase and acetylcholinesterase activities were found in peak I, and procoagulant activity was seen in peak II. Phospholipase A2, hemorrhagic, and proteolytic activities were detected in peak III. A second procoagulant factor and proteinase were present in peak IV. Thrombin-like enzyme and direct hemolytic activities were not found in any assayed samples |
| Disciplinas: | Biología |
| Palabras clave: | Reptiles, Bioquímica, Veneno de víbora, Composición química, Fosfolipasa A2, Acetilcolinesterasa, Fosfatasa alcalina, Micrurus spixii, Elapidae |
| Keyword: | Biology, Reptiles, Biochemistry, Snake venom, Chemical composition, Phospholipase A2, Acetylcholinesterase, Alkaline phosphatase, Micrurus spixii, Elapidae |
| Texte intégral: | Texto completo (Ver HTML) |
