Micrurus spixii (peruvian coral snake) venom - preliminary biochemical and enzymatic characterization



Título del documento: Micrurus spixii (peruvian coral snake) venom - preliminary biochemical and enzymatic characterization
Revista: The journal of venomous animals and toxins
Base de datos: PERIÓDICA
Número de sistema: 000298768
ISSN: 0104-7930
Autores: 1



Instituciones: 1Universidad Nacional Mayor de San Marcos, Facultad de Ciencias Biológicas, Lima. Perú
Año:
Volumen: 8
Número: 1
Paginación: 161-167
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en inglés Micrurus spixii venom was studied after fractionation by Sephadex G-100 SF gel filtration chromatography. Several enzymatic activities and biological effects were investigated in whole venom and fractions. The venom was resolved in four peaks in a range of about 73.2-10.7 kDa molecular weight. Alkaline phosphatase and acetylcholinesterase activities were found in peak I, and procoagulant activity was seen in peak II. Phospholipase A2, hemorrhagic, and proteolytic activities were detected in peak III. A second procoagulant factor and proteinase were present in peak IV. Thrombin-like enzyme and direct hemolytic activities were not found in any assayed samples
Disciplinas: Biología
Palabras clave: Reptiles,
Bioquímica,
Veneno de víbora,
Composición química,
Fosfolipasa A2,
Acetilcolinesterasa,
Fosfatasa alcalina,
Micrurus spixii,
Elapidae
Keyword: Biology,
Reptiles,
Biochemistry,
Snake venom,
Chemical composition,
Phospholipase A2,
Acetylcholinesterase,
Alkaline phosphatase,
Micrurus spixii,
Elapidae
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