| Revista: | Revista médica del Hospital General de México |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000439485 |
| ISSN: | 0185-1063 |
| Autores: | Nuche Bricaire, Avril J1 Trejo Martínez, David2 González García, Nadia3 Contreras Lizardo, Oscar2 Marcos Ortega, José2 Ansaldo Ana I4 González Gómez, Luis2 Mendoza Alavez, Eli2 Silva Pereyra, Juan1 |
| Instituciones: | 1Universidad Nacional Autónoma de México, Facultad de Estudios Superiores Iztacala, Los Reyes Iztacala, Estado de México. México 2Hospital General de México, Departamento de Neurolingüística, Ciudad de México. México 3Hospital Infantil de México "Federico Gómez", Laboratorio de Neurociencias, Ciudad de México. México 4Institut Universitaire de Geriatrie de Montreal, Centre de Recherche, Montreal, Quebec. Canadá |
| Año: | 2019 |
| Periodo: | Ene-Mar |
| Volumen: | 82 |
| Número: | 1 |
| Paginación: | 22-32 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Hemispheric asymmetry reduction in older adults (HAROLD) model has claimed that older adults tend to display less lateralized brain activation patterns with respect to younger ones during memory, language, and naming tasks, but only a few times have these patterns been explored within older population. Furthermore, it is unclear if this phenomenon is a compensation response or an adaptive pattern that is not helping cognitive functions. Literature has assumed that education level (EL) could be critical, to explain such patterns. We aimed to control this as a variable by comparing neural correlates with an functional magnetic resonance imaging picture naming task in literate, healthy older adults with high and low EL. Our results showed that EL is not a determinant factor for activation of neural pattern reorganization prognosis. It was found that performance is a more reliable variable to observe neural pattern reorganization in the elderly. This study supports the de-differentiation hypothesis of HAROLD model because there is no reduction in lateralization of some highly-specialized structures in persons who maintained optimal lexical access, in contrast to those who had low scores in naming task |
| Disciplinas: | Medicina |
| Palabras clave: | Neurología, Geriatría, Ancianos, Asimetría hemisférica, Nivel educativo, Resonancia magnética funcional, Reserva cognitiva |
| Keyword: | Neurology, Geriatrics, Aged, Hemispheric asymmetry, Educational level, Functional magnetic resonance, Cognitive reserve |
| Texto completo: | https://www.hospitalgeneral.mx/frame_esp.php?id=17 |
