| Revue: | Revista médica de Chile |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000455006 |
| ISSN: | 0034-9887 |
| Autores: | Briones, Eduardo1 Méndez, Gonzalo P1 Laguna, Jorge1 Vargas, Miguel2 |
| Instituciones: | 1Clínica Indisa, Santiago de Chile. Chile 2Merkén Biotech, Santiago de Chile. Chile |
| Año: | 2022 |
| Periodo: | Jun |
| Volumen: | 150 |
| Número: | 6 |
| Paginación: | 828-831 |
| País: | Chile |
| Idioma: | Español |
| Tipo de documento: | Artículo |
| Enfoque: | Caso clínico |
| Resumen en inglés | Renal involvement in COVID-19 infection is varied and worsens its outcome and prognosis. However, the association of COVID-19 infection with glomerulonephritis is exceptional. We report a 46-year-old woman with COVID-19 who had an acute kidney injury and ANCA associated glomerulonephritis two weeks after the onset of the disease. The kidney biopsy showed a crescentic glomerulo-nephritis and the presence of anti-glomerular basement membrane antibodies (GBM-Abs). She was treated with steroids and oral cyclophosphamide with good response without requiring plasmapheresis. Plasma anti GBM-Abs were negative. This case suggests that the presence of anti-GBM-Abs in the kidney, was temporally related to COVID-19 pulmonary damage. The absence of plasma antibodies is probably due to transient production and glomerular adsorption, but with unknown pathogenic role |
| Disciplinas: | Medicina |
| Palabras clave: | Nefrología, Inmunología, Anticuerpos citoplásmicos antineutrófilos, Enfermedad anti-glomerular de la membrana basal, COVID-19, Glomerulonefritis, Plasmaféresis |
| Keyword: | Nephrology, Immunology, Antineutrophil cytoplasmic antibodies, Anti-glomerular basement membrane disease, COVID-19, Glomerulonephritis, Plasmapheresis |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
