| Revue: | Revista de investigación clínica |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000453202 |
| ISSN: | 0034-8376 |
| Autores: | Bazán Rodríguez, Lisette1 Cruz Vicioso, Rossy2 Cervantes Arriaga, Amin3 Alcocer Salas, Angel3 Pinto Solís, Daniella3 Rodríguez Violante, Mayela3 |
| Instituciones: | 1Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Departamento de Neurología, Ciudad de México. México 2Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Clínica de Trastornos del Movimiento, Ciudad de México. México 3Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Unidad de Investigación Clínica Neurodegenerativa, Ciudad de México. México |
| Año: | 2020 |
| Periodo: | Sep-Oct |
| Volumen: | 72 |
| Número: | 5 |
| Paginación: | 293-299 |
| País: | México |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Background: People with Parkinson’s disease (PwP) are at higher risk of developing malnutrition. Several factors have been suggested to be involved including motor symptoms, non-motor symptoms, and treatment-related complications. Objective: The objective of the study was to analyze the combined effect of motor, non-motor, and pharmacological factors in the risk of malnutrition in PwP. Methods: Eighty-seven consecutive PwP were included in the study. Clinical data and pharmacological treatment were collected. Nutritional status was assessed using the Mini-Nutritional Assessment (MNA) questionnaire. Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), Non-motor Symptoms Scale (NMSS), Hamilton Depression Rating Scale HAM-D, and Montreal Cognitive Assessment were applied. Results: Thirty (34.4%) PwP were at risk of malnutrition and seven had malnutrition (8%). Abnormal nutritional status was associated with lower education, higher MDS-UPDRS Parts I, II, and III and total scores, and higher scores in the NMSS domain of sleep disorders and fatigue. MDS-UPDRS motor score remained as a determinant of abnormal nutritional status, defined as MNA <23.5, with an odds ratio 1.1 (95% confidence interval 1.01-1.10, p = 0.02). Conclusion: The main factor associated with nutritional status was severity of the motor symptoms as assessed by the MDS-UPDRS Part III. Non-motor symptoms and treatment-related complications were not associated with malnutrition |
| Disciplinas: | Medicina |
| Palabras clave: | Neurología, Metabolismo y nutrición, Enfermedad de Parkinson, Desnutrición, Síntomas motores, Depresión, Demencia |
| Keyword: | Neurology, Metabolism and nutrition, Parkinson disease, Malnutrition, Motor symptoms, Depression, Dementia |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
