| Revue: | Revista brasileira de hematologia e hemoterapia |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000305923 |
| ISSN: | 1516-8484 |
| Autores: | Bahia, Daniella M.M1 Chauffaille, Maria L.F Romeo, Maura S Dias-Silva, Magnus R Kerbauy, Jose |
| Instituciones: | 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo. Brasil |
| Año: | 2002 |
| Periodo: | Abr-Jun |
| Volumen: | 24 |
| Número: | 2 |
| Paginación: | 137-138 |
| País: | Brasil |
| Idioma: | Portugués |
| Tipo de documento: | Correspondencia |
| Enfoque: | Caso clínico |
| Resumen en inglés | Acute leukemia following treatment with Iodine131 is a rare event. The possible carcinogenic effect of Iodine131 is still not clear and a large series of cases did not show an increased incidence of cancer. A case of AML t(8;21), three years after Iodine131 treatment for hyperthyroidism, is reported. Secondary AML with t(8;21) is described following exposure to drugs that target topoisomerase II and radiotherapy. The controversial potential of Iodine131 as a leukemogenic agent and the fact that t(8;21) is also found in de-novo AML, emphasize the problem in establishing a relationship between these events although this potential can not be ruled out |
| Disciplinas: | Medicina |
| Palabras clave: | Hematología, Leucemia mieloide aguda, Hipertiroidismo, Iodo radioactivo |
| Keyword: | Medicine, Hematology, Acute myeloid leukemia, Hyperthyroidism, Radioactive iodine |
| Texte intégral: | Texto completo (Ver HTML) |
