| Journal: | Revista brasileira de hematologia e hemoterapia |
| Database: | PERIÓDICA |
| System number: | 000305923 |
| ISSN: | 1516-8484 |
| Authors: | Bahia, Daniella M.M1 Chauffaille, Maria L.F Romeo, Maura S Dias-Silva, Magnus R Kerbauy, Jose |
| Institutions: | 1Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Sao Paulo. Brasil |
| Year: | 2002 |
| Season: | Abr-Jun |
| Volumen: | 24 |
| Number: | 2 |
| Pages: | 137-138 |
| Country: | Brasil |
| Language: | Portugués |
| Document type: | Correspondencia |
| Approach: | Caso clínico |
| English abstract | Acute leukemia following treatment with Iodine131 is a rare event. The possible carcinogenic effect of Iodine131 is still not clear and a large series of cases did not show an increased incidence of cancer. A case of AML t(8;21), three years after Iodine131 treatment for hyperthyroidism, is reported. Secondary AML with t(8;21) is described following exposure to drugs that target topoisomerase II and radiotherapy. The controversial potential of Iodine131 as a leukemogenic agent and the fact that t(8;21) is also found in de-novo AML, emphasize the problem in establishing a relationship between these events although this potential can not be ruled out |
| Disciplines: | Medicina |
| Keyword: | Hematología, Leucemia mieloide aguda, Hipertiroidismo, Iodo radioactivo |
| Keyword: | Medicine, Hematology, Acute myeloid leukemia, Hyperthyroidism, Radioactive iodine |
| Full text: | Texto completo (Ver HTML) |
