| Revue: | Memorias do Instituto Oswaldo Cruz |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000459453 |
| ISSN: | 0074-0276 |
| Autores: | Gregianini, Tatiana Schäffer1 Salvato, Richard Steiner1 Barcellos, Regina Bones1 Godinho, Fernanda Marques1 Ruivo, Amanda Pellenz1 de Melo, Viviane Horn1 Schroder, Júlio Augusto1 Martiny, Fernanda Letícia1 Möllmann, Erica Bortoli1 Favreto, Cátia1 Baethgen, Ludmila Fiorenzano1 Ferreira, Vithoria Pompermaier1 de Lima, Lívia Eidt1 Piazza, Cláudia Fasolo1 Machado, Taís Raquel Marcon1 Becker, Irina Marieta1 Ramos, Raquel Rocha1 Frölich, Guilherme Carey1 Rossetti, Alana Fraga1 Almeida, Lucas da Cunha1 Rodrigues, Tahiana Machado Antunes1 Bragança, Isabella Tabelli1 Campos, Aline Alves Scarpellini1 Manzoni, Verônica Baú2 Machado, Lais Ceschini3 da Silva, Luisa Maria Inácio3 de Oliveira, André Luiz Sá3 Paiva, Marcelo Henrique Santos3 Nunes, Zenaida Marion Alves1 de Almeida, Paula Rodrigues4 Demoliner, Meriane4 Gularte, Juliana Schons4 da Silva, Mariana Soares4 Filippi, Micheli4 Pereira, Vyctoria Malayhka de Abreu Góes4 Spilki, Fernando Rosado4 da Veiga, Ana Beatriz Gorini5 Wallau, Gabriel Luz3 |
| Instituciones: | 1Secretaria Estadual da Saude do Rio Grande do Sul, Centro Estadual de Vigilancia em Saude, Porto Alegre, Rio Grande do Sul. Brasil 2Prefeitura Municipal de Sao Nicolau, Secretaria Municipal de Sade, Sao Nicolau, Rio Grande do Sul. Brasil 3Fundacao Oswaldo Cruz, Instituto Aggeu Magalhaes, Recife, Pernambuco. Brasil 4Universidade Feevale, Laboratorio de Microbiologia Molecular, Novo Hamburgo, Rio Grande do Sul. Brasil 5Universidade Federal de Ciencias da Saude de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil |
| Año: | 2023 |
| Volumen: | 118 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Chikungunya is a mosquito-borne virus that has been causing large outbreaks in the Americas since 2014. In Brazil, Asian-Caribbean (AC) and East-Central-South-African (ECSA) genotypes have been detected and lead to large outbreaks in several Brazilian states. In Rio Grande do Sul (RS), the southernmost state of Brazil, the first cases were reported in 2016. OBJECTIVES AND METHODS We employed genome sequencing and epidemiological investigation to characterise the Chikungunya fever (CHIKF) burden in RS between 2017-2021. FINDINGS We detected an increasing CHIKF burden linked to travel associated introductions and communitary transmission of distinct lineages of the ECSA genotype during this period. MAIN CONCLUSIONS Until 2020, CHIKV introductions were most travel associated and transmission was limited. Then, in 2021, the largest outbreak occurred in the state associated with the introduction of a new ECSA lineage. CHIKV outbreaks are likely to occur in the near future due to abundant competent vectors and a susceptible population, exposing more than 11 million inhabitants to an increasing infection risk |
| Disciplinas: | Medicina |
| Palabras clave: | Salud pública, Virus, Vigilancia epidemiológica, Arbovirus, Alfavirus, Carga de enfermedad, Brotes, Genómica, Cambio climático, Virus Chikungunya |
| Keyword: | Public health, Virus, Epidemiological surveillance, Arbovirus, Alphavirus, Disease burden, Chikungunya virus, Outbreak, Genomics, Climate change |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
