Chikungunya virus infection in the southernmost state of Brazil was characterised by self-limited transmission (2017-2019) and a larger 2021 outbreak



Título del documento: Chikungunya virus infection in the southernmost state of Brazil was characterised by self-limited transmission (2017-2019) and a larger 2021 outbreak
Revista: Memorias do Instituto Oswaldo Cruz
Base de datos: PERIÓDICA
Número de sistema: 000459453
ISSN: 0074-0276
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Instituciones: 1Secretaria Estadual da Saude do Rio Grande do Sul, Centro Estadual de Vigilancia em Saude, Porto Alegre, Rio Grande do Sul. Brasil
2Prefeitura Municipal de Sao Nicolau, Secretaria Municipal de Sade, Sao Nicolau, Rio Grande do Sul. Brasil
3Fundacao Oswaldo Cruz, Instituto Aggeu Magalhaes, Recife, Pernambuco. Brasil
4Universidade Feevale, Laboratorio de Microbiologia Molecular, Novo Hamburgo, Rio Grande do Sul. Brasil
5Universidade Federal de Ciencias da Saude de Porto Alegre, Porto Alegre, Rio Grande do Sul. Brasil
Año:
Volumen: 118
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Chikungunya is a mosquito-borne virus that has been causing large outbreaks in the Americas since 2014. In Brazil, Asian-Caribbean (AC) and East-Central-South-African (ECSA) genotypes have been detected and lead to large outbreaks in several Brazilian states. In Rio Grande do Sul (RS), the southernmost state of Brazil, the first cases were reported in 2016. OBJECTIVES AND METHODS We employed genome sequencing and epidemiological investigation to characterise the Chikungunya fever (CHIKF) burden in RS between 2017-2021. FINDINGS We detected an increasing CHIKF burden linked to travel associated introductions and communitary transmission of distinct lineages of the ECSA genotype during this period. MAIN CONCLUSIONS Until 2020, CHIKV introductions were most travel associated and transmission was limited. Then, in 2021, the largest outbreak occurred in the state associated with the introduction of a new ECSA lineage. CHIKV outbreaks are likely to occur in the near future due to abundant competent vectors and a susceptible population, exposing more than 11 million inhabitants to an increasing infection risk
Disciplinas: Medicina
Palabras clave: Salud pública,
Virus,
Vigilancia epidemiológica,
Arbovirus,
Alfavirus,
Carga de enfermedad,
Brotes,
Genómica,
Cambio climático,
Virus Chikungunya
Keyword: Public health,
Virus,
Epidemiological surveillance,
Arbovirus,
Alphavirus,
Disease burden,
Chikungunya virus,
Outbreak,
Genomics,
Climate change
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