Efficient Synthesis of 1,5-disubstituted-1H-tetrazoles by an Ugi-azide Process
Título del documento: Efficient Synthesis of 1,5-disubstituted-1H-tetrazoles by an Ugi-azide Process
Revue: Journal of the Mexican Chemical Society
Base de datos: PERIÓDICA
Número de sistema: 000373046
ISSN: 1665-9686
Autores: 1
1
1
2
1
Instituciones: 1Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Guanajuato. México
2Ecole Nationale Supérieure de Techniques Avancees, Laboratoire Chimie et Procedes, París. Francia
Año:
Periodo: Oct-Dic
Volumen: 57
Número: 4
Paginación: 283-289
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental
Resumen en español A series of eighteen novel 1,5-disubstituted-1H-tetrazoles has been prepared with moderate to good overall yields using an Ugi-azide reaction as key step under mild conditions. Tetrazoles are heterocyclic systems present in several synthetic products which have privileged biological activity. Therefore, in this paper we describe the synthesis of novel compounds containing the tetrazole moiety, which could present biological activity
Resumen en inglés A series of eighteen novel 1,5-disubstituted-1H-tetrazoles has been prepared with moderate to good overall yields using an Ugi-azide reaction as key step under mild conditions. Tetrazoles are heterocyclic systems present in several synthetic products which have privileged biological activity. Therefore, in this paper we describe the synthesis of novel compounds containing the tetrazole moiety, which could present biological activity
Disciplinas: Química
Palabras clave: Bioquímica,
Química farmacéutica,
Química orgánica,
Reacciones de multicomponentes,
Ugi-azida,
Electrociclización 1,5 dipolar,
Tetrazoles,
Azida,
Isonitrilo
Keyword: Chemistry,
Biochemistry,
Medicinal chemistry,
Organic chemistry,
Multicomponent reactions,
Ugi-azide,
1,5 dipolar electrocyclization,
Tetrazoles,
Azide,
Isocyanide
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