Efficient Synthesis of 1,5-disubstituted-1H-tetrazoles by an Ugi-azide Process
Document title: Efficient Synthesis of 1,5-disubstituted-1H-tetrazoles by an Ugi-azide Process
Journal: Journal of the Mexican Chemical Society
Database: PERIÓDICA
System number: 000373046
ISSN: 1665-9686
Authors: 1
1
1
2
1
Institutions: 1Universidad de Guanajuato, División de Ciencias Naturales y Exactas, Guanajuato. México
2Ecole Nationale Supérieure de Techniques Avancees, Laboratoire Chimie et Procedes, París. Francia
Year:
Season: Oct-Dic
Volumen: 57
Number: 4
Pages: 283-289
Country: México
Language: Inglés
Document type: Artículo
Approach: Experimental
Spanish abstract A series of eighteen novel 1,5-disubstituted-1H-tetrazoles has been prepared with moderate to good overall yields using an Ugi-azide reaction as key step under mild conditions. Tetrazoles are heterocyclic systems present in several synthetic products which have privileged biological activity. Therefore, in this paper we describe the synthesis of novel compounds containing the tetrazole moiety, which could present biological activity
English abstract A series of eighteen novel 1,5-disubstituted-1H-tetrazoles has been prepared with moderate to good overall yields using an Ugi-azide reaction as key step under mild conditions. Tetrazoles are heterocyclic systems present in several synthetic products which have privileged biological activity. Therefore, in this paper we describe the synthesis of novel compounds containing the tetrazole moiety, which could present biological activity
Disciplines: Química
Keyword: Bioquímica,
Química farmacéutica,
Química orgánica,
Reacciones de multicomponentes,
Ugi-azida,
Electrociclización 1,5 dipolar,
Tetrazoles,
Azida,
Isonitrilo
Keyword: Chemistry,
Biochemistry,
Medicinal chemistry,
Organic chemistry,
Multicomponent reactions,
Ugi-azide,
1,5 dipolar electrocyclization,
Tetrazoles,
Azide,
Isocyanide
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