| Revista: | International braz j urol |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000434653 |
| ISSN: | 1677-5538 |
| Autores: | Ilktac, Abdullah1 Dogan, Bayram1 Ersoz, Cevper1 Akcay, Muzaffer1 Akbulut, Habib1 |
| Instituciones: | 1Bezmialem Vakif University, Faculty of Medicine, Estambul. Turquía |
| Año: | 2020 |
| Periodo: | Ene-Feb |
| Volumen: | 46 |
| Número: | 1 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Aplicado, descriptivo |
| Resumen en inglés | Purpose: To assess the relationship between testicular germ cell tumors (TGCT) and neutrophil to lymphocyte ratio (NLR) and to determine whether this ratio can be used as a serum tumor marker. Material and Methods: Sixty-one patients with testicular germ cell tumors were included into the study. Patients were grouped as localized and non-localized. Histologically patients were categorized as seminoma and nonseminomatous germ cell tumors. Complete blood cell count was measured the day before surgery and at the postoperative 1st month. Preoperative and postoperative mean NLR values were compared. Results: Thirty-six patients (59%) had seminomas and 25 patients (41%) had nonseminomatous testicular cancer. Forty-five patients (73.8%) had localized and 16 patients (26.2%) had non-localized testicular cancer. There was a statistically significant difference between preoperative and postoperative mean NLR of the localized patients (p=0.001) but no such difference was detected for non-localized patients (p=0.576). Nineteen patients with localized seminomas had normal preoperative serum tumor markers. There was a significant difference between preoperative and postoperative mean NLR in this group of patients (p=0.010). Twenty-six patients with localized tumors had preoperative increased serum tumor markers which normalized after orchiectomy. Mean NLR of these patients significantly decreased from 3.10±2.13 to 1.62±0.59 postoperatively (p=0.010). Conclusions: NLR appears to be a useful marker for TGCT. It is successful in predicting localized and non-localized disease in early postoperative period |
| Disciplinas: | Medicina |
| Palabras clave: | Oncología, Urología, Diagnóstico, Tumor testicular de células germinales, Marcadores tumorales, Relación neutrófilos-linfocitos, Orquiectomía |
| Keyword: | Oncology, Urology, Diagnosis, Testicular germ cells tumor, Tumor markers, Orchiectomy, Neutrophil-lymphocyte ratio |
| Texto completo: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
