Technique of kidney transplantation in mice with anti-reflux urinary reconstruction



Título del documento: Technique of kidney transplantation in mice with anti-reflux urinary reconstruction
Revue: International braz j urol
Base de datos: PERIÓDICA
Número de sistema: 000296866
ISSN: 1677-5538
Autores: 1
Instituciones: 1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Estados Unidos de América
Año:
Periodo: Nov-Dic
Volumen: 32
Número: 6
Paginación: 713-720
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Experimental, analítico
Resumen en inglés Experimental models of organ transplantation play a crucial role in establishing the principles of transplantation immunobiology. Murine transplant models of vascularized organs are particularly useful for immunobiological studies because there are more immunological tools available. However, the technique of kidney transplant in mice is very challenging. A difficult aspect of this model is urinary reconstruction, which is frequently associated to complications. In this article, the technique of mouse kidney transplantation using an anti-reflux system (modified extravesical ureteroneocystostomy) is described and illustrated for the first time. Although technically demanding, this procedure is feasible and may reduce the incidence of urine leakage and reflux
Disciplinas: Medicina
Palabras clave: Cirugía,
Medicina experimental,
Trasplantes,
Ratones,
Modelos experimentales,
Microcirugía
Keyword: Medicine,
Experimental medicine,
Surgery,
Transplantation,
Mice,
Experimental models,
Microsurgery
Texte intégral: Texto completo (Ver HTML)