Revue: | International braz j urol |
Base de datos: | PERIÓDICA |
Número de sistema: | 000296866 |
ISSN: | 1677-5538 |
Autores: | Martins, Paulo N1 |
Instituciones: | 1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Estados Unidos de América |
Año: | 2006 |
Periodo: | Nov-Dic |
Volumen: | 32 |
Número: | 6 |
Paginación: | 713-720 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, analítico |
Resumen en inglés | Experimental models of organ transplantation play a crucial role in establishing the principles of transplantation immunobiology. Murine transplant models of vascularized organs are particularly useful for immunobiological studies because there are more immunological tools available. However, the technique of kidney transplant in mice is very challenging. A difficult aspect of this model is urinary reconstruction, which is frequently associated to complications. In this article, the technique of mouse kidney transplantation using an anti-reflux system (modified extravesical ureteroneocystostomy) is described and illustrated for the first time. Although technically demanding, this procedure is feasible and may reduce the incidence of urine leakage and reflux |
Disciplinas: | Medicina |
Palabras clave: | Cirugía, Medicina experimental, Trasplantes, Ratones, Modelos experimentales, Microcirugía |
Keyword: | Medicine, Experimental medicine, Surgery, Transplantation, Mice, Experimental models, Microsurgery |
Texte intégral: | Texto completo (Ver HTML) |