Technique of kidney transplantation in mice with anti-reflux urinary reconstruction



Document title: Technique of kidney transplantation in mice with anti-reflux urinary reconstruction
Journal: International braz j urol
Database: PERIÓDICA
System number: 000296866
ISSN: 1677-5538
Authors: 1
Institutions: 1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Estados Unidos de América
Year:
Season: Nov-Dic
Volumen: 32
Number: 6
Pages: 713-720
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, analítico
English abstract Experimental models of organ transplantation play a crucial role in establishing the principles of transplantation immunobiology. Murine transplant models of vascularized organs are particularly useful for immunobiological studies because there are more immunological tools available. However, the technique of kidney transplant in mice is very challenging. A difficult aspect of this model is urinary reconstruction, which is frequently associated to complications. In this article, the technique of mouse kidney transplantation using an anti-reflux system (modified extravesical ureteroneocystostomy) is described and illustrated for the first time. Although technically demanding, this procedure is feasible and may reduce the incidence of urine leakage and reflux
Disciplines: Medicina
Keyword: Cirugía,
Medicina experimental,
Trasplantes,
Ratones,
Modelos experimentales,
Microcirugía
Keyword: Medicine,
Experimental medicine,
Surgery,
Transplantation,
Mice,
Experimental models,
Microsurgery
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