Wavelet-domain elastic net for clustering on genomes strains



Título del documento: Wavelet-domain elastic net for clustering on genomes strains
Revue: Genetics and molecular biology
Base de datos: PERIÓDICA
Número de sistema: 000424690
ISSN: 1415-4757
Autores: 1
2
3
Instituciones: 1Universidade Federal de Lavras, Programa de Pós-Graduação em Estatística e Experimentação Agropecuária, Lavras, Minas Gerais. Brasil
2Universidade Federal de Lavras, Departamento de Estatistica, Lavras, Minas Gerais. Brasil
3Empresa Brasileira de Pesquisa Agropecuaria, Bage, Rio Grande do Sul. Brasil
Año:
Periodo: Dic
Volumen: 41
Número: 4
Paginación: 884-892
País: Brasil
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés Abstract We propose to evaluate genome similarity by combining discrete non-decimated wavelet transform (NDWT) andelastic net. The wavelets represent a signal with levels of detail, that is, hidden components are detected by means ofthe decomposition of this signal, where each level provides a different characteristic. The main feature of the elastic net is the grouping of correlated variables where the number of predictors is greater than the number of observations.The combination of these two methodologies applied in the clustering analysis of the Mycobacterium tuberculosis genome strains proved very effective, being able to identify clusters at each level of decomposition
Disciplinas: Medicina,
Matemáticas
Palabras clave: Microbiología,
Genética,
Matemáticas aplicadas,
Red elástica,
Genoma,
Mycobacterium tuberculosis,
Contenido de GC,
Análisis de cluster,
Transformada Wavelet
Keyword: Microbiology,
Genetics,
Applied mathematics,
Elastic net,
Genome,
GC content,
Mycobacterium tuberculosis,
Cluster analysis,
Wavelet transform
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