Wavelet-domain elastic net for clustering on genomes strains



Document title: Wavelet-domain elastic net for clustering on genomes strains
Journal: Genetics and molecular biology
Database: PERIÓDICA
System number: 000424690
ISSN: 1415-4757
Authors: 1
2
3
Institutions: 1Universidade Federal de Lavras, Programa de Pós-Graduação em Estatística e Experimentação Agropecuária, Lavras, Minas Gerais. Brasil
2Universidade Federal de Lavras, Departamento de Estatistica, Lavras, Minas Gerais. Brasil
3Empresa Brasileira de Pesquisa Agropecuaria, Bage, Rio Grande do Sul. Brasil
Year:
Season: Dic
Volumen: 41
Number: 4
Pages: 884-892
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Analítico, descriptivo
English abstract Abstract We propose to evaluate genome similarity by combining discrete non-decimated wavelet transform (NDWT) andelastic net. The wavelets represent a signal with levels of detail, that is, hidden components are detected by means ofthe decomposition of this signal, where each level provides a different characteristic. The main feature of the elastic net is the grouping of correlated variables where the number of predictors is greater than the number of observations.The combination of these two methodologies applied in the clustering analysis of the Mycobacterium tuberculosis genome strains proved very effective, being able to identify clusters at each level of decomposition
Disciplines: Medicina,
Matemáticas
Keyword: Microbiología,
Genética,
Matemáticas aplicadas,
Red elástica,
Genoma,
Mycobacterium tuberculosis,
Contenido de GC,
Análisis de cluster,
Transformada Wavelet
Keyword: Microbiology,
Genetics,
Applied mathematics,
Elastic net,
Genome,
GC content,
Mycobacterium tuberculosis,
Cluster analysis,
Wavelet transform
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