| Revue: | Genetics and molecular biology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000459164 |
| ISSN: | 1415-4757 |
| Autores: | Hespanhol, Julia Takuno1 Karman, Lior1 Sanchez Limache, Daniel Enrique1 Bayer Santos, Ethel1 |
| Instituciones: | 1Universidade de Sao Paulo, Instituto de Ciencias Biomedicas, Sao Paulo. Brasil |
| Año: | 2023 |
| Volumen: | 46 |
| Número: | 1 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Descriptivo |
| Resumen en inglés | Bacteria live in polymicrobial communities and constantly compete for resources. These organisms have evolved an array of antibacterial weapons to inhibit the growth or kill competitors. The arsenal comprises antibiotics, bacteriocins, and contact-dependent effectors that are either secreted in the medium or directly translocated into target cells. During bacterial antagonistic encounters, several cellular components important for life become a weak spot prone to an attack. Nucleic acids and the machinery responsible for their synthesis are well conserved across the tree of life. These molecules are part of the information flow in the central dogma of molecular biology and mediate long- and short-term storage for genetic information. The aim of this review is to summarize the diversity of antibacterial molecules that target nucleic acids during antagonistic interbacterial encounters and discuss their potential to promote the emergence antibiotic resistance |
| Disciplinas: | Biología |
| Palabras clave: | Genética, Bacterias, Antibióticos, Revisión bibliográfica, Moléculas antibacterianas |
| Keyword: | Genetics, Bacteria, Antibiotics, Bibliographic review, Antibacterial molecules |
| Texte intégral: | Texto completo (Ver HTML) Texto completo (Ver PDF) |
