Revue: | Brazilian archives of biology and technology |
Base de datos: | PERIÓDICA |
Número de sistema: | 000362759 |
ISSN: | 1516-8913 |
Autores: | EL-Toweissy, Mona Yossef1 Mohamed, Nema Abdel-Hameed1 Abdel-Wahab, Wessam Mohamed1 |
Instituciones: | 1Alexandria University, Faculty of Science, Alejandría. Egipto |
Año: | 2013 |
Periodo: | May-Jun |
Volumen: | 56 |
Número: | 3 |
Paginación: | 393-404 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Experimental, aplicado |
Resumen en inglés | This study was undertaken to determine the modulating effects of intramuscular administration of melatonin (MT)(1mg/ kg) and/or Tri-B (B 1 , B 6 and B 12 ) (20mg/kg) on body weight and some biochemical changes in rats induced by Epinephrine (Epi) injection. The data showed that MT and/or Tri-B treatment effectively improved the changes in malondialdehyde, lipid profile, blood sugar level and insulin. MT and/or Tri-B administration following Epi improved partially the decrease in body weight and liver glycogen levels. Tri B injection following Epi partialy improved all the tested parameters except malondialdehyde and blood sugar level that completely improved in stressed rats. It was evident that a combination of MT and vitamin B complex had protective actions and further it was better than either of them introduced alone in stressed rats. The possible interaction between MT and Tri B provided further support to MT synergistic actions with the aim of advocating MT and Tri B as a possible synergistic therapy |
Disciplinas: | Medicina |
Palabras clave: | Farmacología, Medicina experimental, Estrés, Melatonina, Vitamina B1, Vitamina B6, Vitamina B12 |
Keyword: | Medicine, Experimental medicine, Pharmacology, Stress, Melatonin, Vitamin B1, Vitamin B6, Vitamin B12 |
Texte intégral: | Texto completo (Ver HTML) |