| Revista: | Brazilian archives of biology and technology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000362759 |
| ISSN: | 1516-8913 |
| Autores: | EL-Toweissy, Mona Yossef1 Mohamed, Nema Abdel-Hameed1 Abdel-Wahab, Wessam Mohamed1 |
| Instituciones: | 1Alexandria University, Faculty of Science, Alejandría. Egipto |
| Año: | 2013 |
| Periodo: | May-Jun |
| Volumen: | 56 |
| Número: | 3 |
| Paginación: | 393-404 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | This study was undertaken to determine the modulating effects of intramuscular administration of melatonin (MT)(1mg/ kg) and/or Tri-B (B 1 , B 6 and B 12 ) (20mg/kg) on body weight and some biochemical changes in rats induced by Epinephrine (Epi) injection. The data showed that MT and/or Tri-B treatment effectively improved the changes in malondialdehyde, lipid profile, blood sugar level and insulin. MT and/or Tri-B administration following Epi improved partially the decrease in body weight and liver glycogen levels. Tri B injection following Epi partialy improved all the tested parameters except malondialdehyde and blood sugar level that completely improved in stressed rats. It was evident that a combination of MT and vitamin B complex had protective actions and further it was better than either of them introduced alone in stressed rats. The possible interaction between MT and Tri B provided further support to MT synergistic actions with the aim of advocating MT and Tri B as a possible synergistic therapy |
| Disciplinas: | Medicina |
| Palabras clave: | Farmacología, Medicina experimental, Estrés, Melatonina, Vitamina B1, Vitamina B6, Vitamina B12 |
| Keyword: | Medicine, Experimental medicine, Pharmacology, Stress, Melatonin, Vitamin B1, Vitamin B6, Vitamin B12 |
| Texto completo: | Texto completo (Ver HTML) |
