| Revue: | Brazilian archives of biology and technology |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000365590 |
| ISSN: | 1516-8913 |
| Autores: | Freitas, Karine Moura de1 Natali, Antônio Jose2 Lunz, Wellington3 Costa, Kyvia Lugate Cardoso2 Leite, Rodrigo Paula1 Dolder, Heidi1 Matta, Sergio Luis Pinto da2 |
| Instituciones: | 1Universidade Estadual de Campinas, Instituto de Biologia, Campinas, Sao Paulo. Brasil 2Universidade Federal de Vicosa, Centro de Ciencias Biologicas e da Saude, Vicosa, Minas Gerais. Brasil 3Universidade Federal do Espirito Santo, Centro de Educacao Fisica e Desportos, Vitoria, Espirito Santo. Brasil |
| Año: | 2013 |
| Periodo: | Jul-Ago |
| Volumen: | 56 |
| Número: | 4 |
| Paginación: | 557-566 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Experimental, aplicado |
| Resumen en inglés | This study was undertaken to determine whether colon cancer (CC) and chronic swimming exercise alter rat testis. Eleven weeks old rats were distributed into control group (n=6) and the groups that were induced to develop CC by dimethylhydrazine injections (nEG, EG0, EG2 and EG4; n=10 each group). In the group nEG, the rats did not swim, whereas groups EG0, EG2 and EG4, underwent a swimming program with distinct loads (0, 2 and 4% of body mass, respectively) for 35 weeks. The morphometry, stereology and cell counts showed damage caused by the CC on the germ epithelium. These results were noteworthy since this was the first report to associate the CC with testicular damage. Swimming exercise had no significant role in reducing, or increasing the CC effects on the testis, despite having slightly improved the testis structure of the exercised rats without load. In conclusion, CC caused testis impairment, which could not be avoided by the swimming exercise |
| Disciplinas: | Biología, Medicina |
| Palabras clave: | Medicina experimental, Oncología, Cáncer, Colon, Daño tisular, Testículos, Espermatogénesis, Ratas |
| Keyword: | Biology, Medicine, Experimental medicine, Oncology, Cancer, Colon, Tissue damage, Testicles, Spermatogenesis, Rats |
| Texte intégral: | Texto completo (Ver HTML) |
