Colon cancer and swimming exercise: effect on wistar rat testes
Document title: Colon cancer and swimming exercise: effect on wistar rat testes
Journal: Brazilian archives of biology and technology
Database: PERIÓDICA
System number: 000365590
ISSN: 1516-8913
Authors: 1
2
3
2
1
1
2
Institutions: 1Universidade Estadual de Campinas, Instituto de Biologia, Campinas, Sao Paulo. Brasil
2Universidade Federal de Vicosa, Centro de Ciencias Biologicas e da Saude, Vicosa, Minas Gerais. Brasil
3Universidade Federal do Espirito Santo, Centro de Educacao Fisica e Desportos, Vitoria, Espirito Santo. Brasil
Year:
Season: Jul-Ago
Volumen: 56
Number: 4
Pages: 557-566
Country: Brasil
Language: Inglés
Document type: Artículo
Approach: Experimental, aplicado
English abstract This study was undertaken to determine whether colon cancer (CC) and chronic swimming exercise alter rat testis. Eleven weeks old rats were distributed into control group (n=6) and the groups that were induced to develop CC by dimethylhydrazine injections (nEG, EG0, EG2 and EG4; n=10 each group). In the group nEG, the rats did not swim, whereas groups EG0, EG2 and EG4, underwent a swimming program with distinct loads (0, 2 and 4% of body mass, respectively) for 35 weeks. The morphometry, stereology and cell counts showed damage caused by the CC on the germ epithelium. These results were noteworthy since this was the first report to associate the CC with testicular damage. Swimming exercise had no significant role in reducing, or increasing the CC effects on the testis, despite having slightly improved the testis structure of the exercised rats without load. In conclusion, CC caused testis impairment, which could not be avoided by the swimming exercise
Disciplines: Biología,
Medicina
Keyword: Medicina experimental,
Oncología,
Cáncer,
Colon,
Daño tisular,
Testículos,
Espermatogénesis,
Ratas
Keyword: Biology,
Medicine,
Experimental medicine,
Oncology,
Cancer,
Colon,
Tissue damage,
Testicles,
Spermatogenesis,
Rats
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