Portal vein thrombosis in patients with cirrhosis: just a common finding or a predictor of poor outcome?



Título del documento: Portal vein thrombosis in patients with cirrhosis: just a common finding or a predictor of poor outcome?
Revue: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000406037
ISSN: 1665-2681
Autores: 1
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Instituciones: 1Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Monterrey, Nuevo León. México
Año:
Periodo: Nov-Dic
Volumen: 15
Número: 6
Paginación: 902-906
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Analítico, descriptivo
Resumen en inglés It Background & Aims. is unclear whether portal vein thrombosis (PVT) unrelated to malignancy is associated with reduced survival or it is an epiphenomenon of advanced cirrhosis. The objective of this study was to assess clinical outcome in cirrhotic patients with PVT not associated with malignancy and determine its prevalence. Material and methods. Material and methods. Material and methods. Retrospective search in one center from June 2011 to December 2014. Results. Results. 169 Results. patients, 55 women and 114 men, median age 54 (19-90) years. Thirteen had PVT (7.6%). None of the patients received anticoagulant treatment. The PVT group was younger (49 [25-62] vs. 55 [19-90] years p = 0.025). Child A patients were more frequent in PVT and Child C in Non-PVT. Median Model for End Stage Liver Disease (MELD) score was lower in PVT (12 [8-21] vs. 19 [7-51] p ≤ 0.001) p ≤ 0.001). There was no difference between upper gastrointestinal bleeding and spontaneous bacterial peritonitis in the groups. Encephalopathy grade 3-4 (4 [30.8%] vs. 73 [46.8%] p = 0,007) and large volume ascites (5 [38.5%] vs. 89 [57.1%] p= 0,012) was more common in non-PVT. Survival was better for PVT (16.5 ± 27.9 vs. 4.13 ± 12.2 months p = 0.005). Conclusions: We found that PVT itself does not lead to a worse prognosis. The most reliable predictor for clinical outcome remains the MELD score. The presence of PVT could be just an epiphenomenon and not a marker of advanced cirrhosis
Disciplinas: Medicina
Palabras clave: Diagnóstico,
Gastroenterología,
Terapéutica y rehabilitación,
Cirrosis hepática,
Trombosis,
Vena portal,
Escala Child-Pugh
Keyword: Medicine,
Diagnosis,
Gastroenterology,
Therapeutics and rehabilitation,
Liver cirrhosis,
Thrombosis,
Portal vein,
Child-Pugh Scale
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