Revista: | Annals of hepatology |
Base de datos: | PERIÓDICA |
Número de sistema: | 000406037 |
ISSN: | 1665-2681 |
Autors: | Borjas Almaguer, Omar D1 Cortez Hernández, Carlos A1 González Moreno, Emmanuel I1 Bosques Padilla, Francisco J1 González González, José A1 Garza, Aldo A1 Martínez Segura, Juan A-1 García Compean, Diego1 Alejandre Loya, Juan V1 García García, Jesús1 Delgado García, Guillermo1 Maldonado Garza, Héctor J1 |
Institucions: | 1Universidad Autónoma de Nuevo León, Hospital Universitario Dr. José Eleuterio González, Monterrey, Nuevo León. México |
Any: | 2016 |
Període: | Nov-Dic |
Volum: | 15 |
Número: | 6 |
Paginació: | 902-906 |
País: | México |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Analítico, descriptivo |
Resumen en inglés | It Background & Aims. is unclear whether portal vein thrombosis (PVT) unrelated to malignancy is associated with reduced survival or it is an epiphenomenon of advanced cirrhosis. The objective of this study was to assess clinical outcome in cirrhotic patients with PVT not associated with malignancy and determine its prevalence. Material and methods. Material and methods. Material and methods. Retrospective search in one center from June 2011 to December 2014. Results. Results. 169 Results. patients, 55 women and 114 men, median age 54 (19-90) years. Thirteen had PVT (7.6%). None of the patients received anticoagulant treatment. The PVT group was younger (49 [25-62] vs. 55 [19-90] years p = 0.025). Child A patients were more frequent in PVT and Child C in Non-PVT. Median Model for End Stage Liver Disease (MELD) score was lower in PVT (12 [8-21] vs. 19 [7-51] p ≤ 0.001) p ≤ 0.001). There was no difference between upper gastrointestinal bleeding and spontaneous bacterial peritonitis in the groups. Encephalopathy grade 3-4 (4 [30.8%] vs. 73 [46.8%] p = 0,007) and large volume ascites (5 [38.5%] vs. 89 [57.1%] p= 0,012) was more common in non-PVT. Survival was better for PVT (16.5 ± 27.9 vs. 4.13 ± 12.2 months p = 0.005). Conclusions: We found that PVT itself does not lead to a worse prognosis. The most reliable predictor for clinical outcome remains the MELD score. The presence of PVT could be just an epiphenomenon and not a marker of advanced cirrhosis |
Disciplines | Medicina |
Paraules clau: | Diagnóstico, Gastroenterología, Terapéutica y rehabilitación, Cirrosis hepática, Trombosis, Vena portal, Escala Child-Pugh |
Keyword: | Medicine, Diagnosis, Gastroenterology, Therapeutics and rehabilitation, Liver cirrhosis, Thrombosis, Portal vein, Child-Pugh Scale |
Text complet: | Texto completo (Ver PDF) |