Albumin dialysis with MARS for the treatment of anabolic steroid-induced cholestasis
Título del documento: Albumin dialysis with MARS for the treatment of anabolic steroid-induced cholestasis
Revue: Annals of hepatology
Base de datos: PERIÓDICA
Número de sistema: 000406049
ISSN: 1665-2681
Autores: 1
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Instituciones: 1Hospital Universitario La Fe, Departamento de Gastroenterología, Valencia. España
2Hospital Universitario La Fe, Departamento de Gastroenterología Pediátrica, Valencia. España
Año:
Periodo: Nov-Dic
Volumen: 15
Número: 6
Paginación: 939-943
País: México
Idioma: Inglés
Tipo de documento: Artículo
Enfoque: Caso clínico, descriptivo
Resumen en inglés Steroid-related hepatotoxicity has become one of the most relevant causes of drug induced liver cholestasis. Some patients do not improve after standard medical treatment (SMT) and may therefore require other approaches, like extracorporeal liver support. Material and methods. Material and methods. We Material and methods. report four cases of patients with pruritus, abnormal liver function tests and biopsy-proven anabolic steroid-induced cholestasis who were unresponsive to SMT. They underwent treatment with albumin dialysis (Molecular Adsorbent Recirculating System -MARS®-). A minimum of two MARS sessions were performed. Results. Results. After MARS® procedure, patients' symptoms improved, as well as liver function tests, thus avoiding liver transplantation. Conclusion. Albumin dialysis appears as a valuable therapeutic option for the management of anabolic steroid-induced cholestasis in patients that are unresponsive to SMT
Disciplinas: Medicina
Palabras clave: Gastroenterología,
Terapéutica y rehabilitación,
Toxicología,
Esteroides anabólicos,
Hepatotoxicidad,
Colestasis,
Falla hepática,
Diálisis,
Albúmina
Keyword: Medicine,
Gastroenterology,
Therapeutics and rehabilitation,
Toxicology,
Anabolic steroids,
Hepatotoxicity,
Cholestasis,
Liver failure,
Dialysis,
Albumin
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