Albumin dialysis with MARS for the treatment of anabolic steroid-induced cholestasis
Document title: Albumin dialysis with MARS for the treatment of anabolic steroid-induced cholestasis
Journal: Annals of hepatology
Database: PERIÓDICA
System number: 000406049
ISSN: 1665-2681
Authors: 1
1
1
1
1
2
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3
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Institutions: 1Hospital Universitario La Fe, Departamento de Gastroenterología, Valencia. España
2Hospital Universitario La Fe, Departamento de Gastroenterología Pediátrica, Valencia. España
Year:
Season: Nov-Dic
Volumen: 15
Number: 6
Pages: 939-943
Country: México
Language: Inglés
Document type: Artículo
Approach: Caso clínico, descriptivo
English abstract Steroid-related hepatotoxicity has become one of the most relevant causes of drug induced liver cholestasis. Some patients do not improve after standard medical treatment (SMT) and may therefore require other approaches, like extracorporeal liver support. Material and methods. Material and methods. We Material and methods. report four cases of patients with pruritus, abnormal liver function tests and biopsy-proven anabolic steroid-induced cholestasis who were unresponsive to SMT. They underwent treatment with albumin dialysis (Molecular Adsorbent Recirculating System -MARS®-). A minimum of two MARS sessions were performed. Results. Results. After MARS® procedure, patients' symptoms improved, as well as liver function tests, thus avoiding liver transplantation. Conclusion. Albumin dialysis appears as a valuable therapeutic option for the management of anabolic steroid-induced cholestasis in patients that are unresponsive to SMT
Disciplines: Medicina
Keyword: Gastroenterología,
Terapéutica y rehabilitación,
Toxicología,
Esteroides anabólicos,
Hepatotoxicidad,
Colestasis,
Falla hepática,
Diálisis,
Albúmina
Keyword: Medicine,
Gastroenterology,
Therapeutics and rehabilitation,
Toxicology,
Anabolic steroids,
Hepatotoxicity,
Cholestasis,
Liver failure,
Dialysis,
Albumin
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