| Revue: | Anais brasileiros de dermatologia |
| Base de datos: | PERIÓDICA |
| Número de sistema: | 000404084 |
| ISSN: | 0365-0596 |
| Autores: | Avancini, Joao1 Sanches, Jose Antonio1 Cherubim, Andre Pires Zanata1 Pazzini, Renato1 Oliveira, Cristina Mendes de1 Sumita, Laura Masami1 Valente, Neusa Yuriko Sakai1 Pannuti, Claudio Sergio1 Festa-Neto, Cyro1 |
| Instituciones: | 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil |
| Año: | 2016 |
| Periodo: | Nov-Dic |
| Volumen: | 91 |
| Número: | 6 |
| Paginación: | 738-742 |
| País: | Brasil |
| Idioma: | Inglés |
| Tipo de documento: | Artículo |
| Enfoque: | Analítico, descriptivo |
| Resumen en inglés | Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma |
| Disciplinas: | Medicina |
| Palabras clave: | Dermatología, Oncología, Virus, Herpesvirus humano-8, VIH, Hemangiosarcoma, Células endoteliales, Sarcoma de Kaposi, Patogénesis |
| Keyword: | Medicine, Dermatology, Oncology, Virus, Human herpesvirus-8, HIV, Hemangiosarcoma, Endothelial cells, Kaposi sarcoma, Pathogenesis |
| Texte intégral: | Texto completo (Ver HTML) |
