Revista: | Anais brasileiros de dermatologia |
Base de datos: | PERIÓDICA |
Número de sistema: | 000404084 |
ISSN: | 0365-0596 |
Autors: | Avancini, Joao1 Sanches, Jose Antonio1 Cherubim, Andre Pires Zanata1 Pazzini, Renato1 Oliveira, Cristina Mendes de1 Sumita, Laura Masami1 Valente, Neusa Yuriko Sakai1 Pannuti, Claudio Sergio1 Festa-Neto, Cyro1 |
Institucions: | 1Universidade de Sao Paulo, Faculdade de Medicina, Sao Paulo. Brasil |
Any: | 2016 |
Període: | Nov-Dic |
Volum: | 91 |
Número: | 6 |
Paginació: | 738-742 |
País: | Brasil |
Idioma: | Inglés |
Tipo de documento: | Artículo |
Enfoque: | Analítico, descriptivo |
Resumen en inglés | Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma |
Disciplines | Medicina |
Paraules clau: | Dermatología, Oncología, Virus, Herpesvirus humano-8, VIH, Hemangiosarcoma, Células endoteliales, Sarcoma de Kaposi, Patogénesis |
Keyword: | Medicine, Dermatology, Oncology, Virus, Human herpesvirus-8, HIV, Hemangiosarcoma, Endothelial cells, Kaposi sarcoma, Pathogenesis |
Text complet: | Texto completo (Ver HTML) |